There are two main game modes in Madden NFL 22 Mobile Football: single player and multiplayer. If you play alone, you will face NPC opponents. This type of single-player game is divided into many different sub-modes, including Madden Today, Programs, Masters Series or Seasons.

The game still retains the classic gameplay of a traditional American soccer game. After selecting a team and game mode, you will accompany the other 10 members of your team as they take turns playing against each other to win the top spot in the tournament. In Competitive mode, you will play against other real players. Each match in this mode is short, lasting up to 3 minutes, and is won or lost at a glance.

In each game, two teams take turns attacking and defending. The winning team is the one that earns more points in the given time period specified for each tournament. At the end of the tournament, the winning team receives the tournament prize.